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In vivo study of the effect of antiviral acyclic nucleotide phosphonate (R)-9-[2-(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its prodrug tenofovir disoproxil fumarate on rat microsomal cytochrome P450

  • E. Anzenbacherová
  • , Pavel Anzenbacher
  • , Z. Zídek
  • , E. Buchar
  • , E. Kmoníčková
  • , P. Potměšil
  • , J. Nekvindová
  • , A. Veinlichová
  • , A. Holý
  • Palacký University
  • Institute of Pharmacology
  • Institute of Experimental Medicine of the Czech Academy of Sciences
  • Flemingovo Nam. 2, 166 10 Prague, C.

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)761-767
Number of pages7
JournalPhysiological Research
Volume57
Issue number5
StatePublished - 2008
Externally publishedYes

ASJC Scopus Subject Areas

  • Physiology

Keywords

  • CYP1A2
  • CYP2E1
  • Cytochrome P450
  • PMPA
  • Tenofovir

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