Sexual minority adults exhibit greater inflammation than heterosexual adults in the context of depressive symptoms and anxiety: Pathways to health disparities

Lisa M. Christian; Rebecca R. Andridge; Juan Peng; Nithya P. Kasibhatla; Thomas W. McDade; Tessa Blevins; Steve W. Cole; Wendy D. Manning; Claire M. Kamp Dush

doi:10.1016/j.bbi.2025.106202

Sexual minority adults exhibit greater inflammation than heterosexual adults in the context of depressive symptoms and anxiety: Pathways to health disparities

Lisa M. Christian
, Rebecca R. Andridge
, Juan Peng
, Nithya P. Kasibhatla
, Thomas W. McDade
, Tessa Blevins
, Steve W. Cole
, Wendy D. Manning
, Claire M. Kamp Dush

Department of Sociology

The Ohio State University Wexner Medical Center
The Ohio State University College of Medicine
Northwestern University
The Ohio State University
UCLA School of Medicine
University of Minnesota Twin Cities

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	106202
Journal	Brain, Behavior, and Immunity
Volume	133
DOIs	https://doi.org/10.1016/j.bbi.2025.106202
State	Published - Mar 2026

ASJC Scopus Subject Areas

Immunology
Endocrine and Autonomic Systems
Behavioral Neuroscience

Keywords

Anxiety
Bisexual
Depression
Depressive symptoms
Gay
Heterosexual
Inflammation
Lesbian
LGBTQ+
Psychological well-being
Sexual minority
Sexually diverse
Stress

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10.1016/j.bbi.2025.106202

Cite this

Christian, L. M., Andridge, R. R., Peng, J., Kasibhatla, N. P., McDade, T. W., Blevins, T., Cole, S. W., Manning, W. D., & Kamp Dush, C. M. (2026). Sexual minority adults exhibit greater inflammation than heterosexual adults in the context of depressive symptoms and anxiety: Pathways to health disparities. Brain, Behavior, and Immunity, 133, Article 106202. https://doi.org/10.1016/j.bbi.2025.106202

Christian, LM, Andridge, RR, Peng, J, Kasibhatla, NP, McDade, TW, Blevins, T, Cole, SW, Manning, WD & Kamp Dush, CM 2026, 'Sexual minority adults exhibit greater inflammation than heterosexual adults in the context of depressive symptoms and anxiety: Pathways to health disparities', Brain, Behavior, and Immunity, vol. 133, 106202. https://doi.org/10.1016/j.bbi.2025.106202

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AU - Kasibhatla, Nithya P.

AU - McDade, Thomas W.

AU - Blevins, Tessa

AU - Cole, Steve W.

AU - Manning, Wendy D.

AU - Kamp Dush, Claire M.

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KW - LGBTQ+

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KW - Sexually diverse

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Sexual minority adults exhibit greater inflammation than heterosexual adults in the context of depressive symptoms and anxiety: Pathways to health disparities

ASJC Scopus Subject Areas

Keywords

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