The toxicity and pharmacokinetics of dihydrosanguinarine in rat: A pilot study

Eva Vrublova; Jitka Vostalova; Rostislav Vecera; Borivoj Klejdus; David Stejskal; Pavel Kosina; Adela Zdarilova; Alena Svobodova; Vaclav Lichnovsky; Pavel Anzenbacher; Zdenek Dvorak; Jaroslav Vicar; Vilim Simanek; Jitka Ulrichova

doi:10.1016/j.fct.2008.04.013

The toxicity and pharmacokinetics of dihydrosanguinarine in rat: A pilot study

Eva Vrublova
, Jitka Vostalova
, Rostislav Vecera
, Borivoj Klejdus
, David Stejskal
, Pavel Kosina
, Adela Zdarilova
, Alena Svobodova
, Vaclav Lichnovsky
, Pavel Anzenbacher
, Zdenek Dvorak
, Jaroslav Vicar
, Vilim Simanek
, Jitka Ulrichova

Palacký University
Mendel University in Brno
Sternberk Hospital
Department of Pharmacology

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2546-2553
Number of pages	8
Journal	Food and Chemical Toxicology
Volume	46
Issue number	7
DOIs	https://doi.org/10.1016/j.fct.2008.04.013
State	Published - Jul 2008
Externally published	Yes

ASJC Scopus Subject Areas

Food Science
Toxicology

Keywords

Benzo[c]phenanthridine alkaloid
Dietary toxicity
Dihydrosanguinarine
Disposition
Metabolism
Sanguinarine

Access to Document

10.1016/j.fct.2008.04.013

Cite this

Vrublova, E., Vostalova, J., Vecera, R., Klejdus, B., Stejskal, D., Kosina, P., Zdarilova, A., Svobodova, A., Lichnovsky, V., Anzenbacher, P., Dvorak, Z., Vicar, J., Simanek, V., & Ulrichova, J. (2008). The toxicity and pharmacokinetics of dihydrosanguinarine in rat: A pilot study. Food and Chemical Toxicology, 46(7), 2546-2553. https://doi.org/10.1016/j.fct.2008.04.013

Vrublova, E, Vostalova, J, Vecera, R, Klejdus, B, Stejskal, D, Kosina, P, Zdarilova, A, Svobodova, A, Lichnovsky, V, Anzenbacher, P, Dvorak, Z, Vicar, J, Simanek, V & Ulrichova, J 2008, 'The toxicity and pharmacokinetics of dihydrosanguinarine in rat: A pilot study', Food and Chemical Toxicology, vol. 46, no. 7, pp. 2546-2553. https://doi.org/10.1016/j.fct.2008.04.013

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title = "The toxicity and pharmacokinetics of dihydrosanguinarine in rat: A pilot study",

keywords = "Benzo[c]phenanthridine alkaloid, Dietary toxicity, Dihydrosanguinarine, Disposition, Metabolism, Sanguinarine",

author = "Eva Vrublova and Jitka Vostalova and Rostislav Vecera and Borivoj Klejdus and David Stejskal and Pavel Kosina and Adela Zdarilova and Alena Svobodova and Vaclav Lichnovsky and Pavel Anzenbacher and Zdenek Dvorak and Jaroslav Vicar and Vilim Simanek and Jitka Ulrichova",

year = "2008",

month = jul,

doi = "10.1016/j.fct.2008.04.013",

language = "English",

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T1 - The toxicity and pharmacokinetics of dihydrosanguinarine in rat

T2 - A pilot study

AU - Vrublova, Eva

AU - Vostalova, Jitka

AU - Vecera, Rostislav

AU - Klejdus, Borivoj

AU - Stejskal, David

AU - Kosina, Pavel

AU - Zdarilova, Adela

AU - Svobodova, Alena

AU - Lichnovsky, Vaclav

AU - Anzenbacher, Pavel

AU - Dvorak, Zdenek

AU - Vicar, Jaroslav

AU - Simanek, Vilim

AU - Ulrichova, Jitka

PY - 2008/7

Y1 - 2008/7

KW - Benzo[c]phenanthridine alkaloid

KW - Dietary toxicity

KW - Dihydrosanguinarine

KW - Disposition

KW - Metabolism

KW - Sanguinarine

UR - https://www.scopus.com/pages/publications/46549083014

UR - https://www.scopus.com/pages/publications/46549083014#tab=citedBy

U2 - 10.1016/j.fct.2008.04.013

DO - 10.1016/j.fct.2008.04.013

M3 - Article

C2 - 18495316

AN - SCOPUS:46549083014

SN - 0278-6915

VL - 46

SP - 2546

EP - 2553

JO - Food and Chemical Toxicology

JF - Food and Chemical Toxicology

IS - 7

ER -

The toxicity and pharmacokinetics of dihydrosanguinarine in rat: A pilot study

ASJC Scopus Subject Areas

Keywords

Access to Document

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