Unraveling the functional dark matter through global metagenomics

Georgios A. Pavlopoulos; Fotis A. Baltoumas; Sirui Liu; Oguz Selvitopi; Antonio Pedro Camargo; Stephen Nayfach; Ariful Azad; Simon Roux; Lee Call; Natalia N. Ivanova; I. Min Chen; David Paez-Espino; Evangelos Karatzas; Silvia G. Acinas; Nathan Ahlgren; Graeme Attwood; Petr Baldrian; Timothy Berry; Jennifer M. Bhatnagar; Devaki Bhaya; Kay D. Bidle; Jeffrey L. Blanchard; Eric S. Boyd; Jennifer L. Bowen; Jeff Bowman; Susan H. Brawley; Eoin L. Brodie; Andreas Brune; Donald A. Bryant; Alison Buchan; Hinsby Cadillo-Quiroz; Barbara J. Campbell; Ricardo Cavicchioli; Peter F. Chuckran; Maureen Coleman; Sean Crowe; Daniel R. Colman; Cameron R. Currie; Jeff Dangl; Nathalie Delherbe; Vincent J. Denef; Paul Dijkstra; Daniel D. Distel; Emiley Eloe-Fadrosh; Kirsten Fisher; Christopher Francis; Aaron Garoutte; Amelie Gaudin; Lena Gerwick; Filipa Godoy-Vitorino; Peter Guerra; Jiarong Guo; Mussie Y. Habteselassie; Steven J. Hallam; Roland Hatzenpichler; Ute Hentschel; Matthias Hess; Ann M. Hirsch; Laura A. Hug; Jenni Hultman; Dana E. Hunt; Marcel Huntemann; William P. Inskeep; Timothy Y. James; Janet Jansson; Eric R. Johnston; Marina Kalyuzhnaya; Charlene N. Kelly; Robert M. Kelly; Jonathan L. Klassen; Klaus Nüsslein; Joel E. Kostka; Steven Lindow; Erik Lilleskov; Mackenzie Lynes; Rachel Mackelprang; Francis M. Martin; Olivia U. Mason; R. Michael McKay; Katherine McMahon; David A. Mead; Monica Medina; Laura K. Meredith; Thomas Mock; William W. Mohn; Mary Ann Moran; Alison Murray; Josh D. Neufeld; Rebecca Neumann; Jeanette M. Norton; Laila P. Partida-Martinez; Nicole Pietrasiak; Dale Pelletier; T. B.K. Reddy; Brandi Kiel Reese; Nicholas J. Reichart; Rebecca Reiss; Mak A. Saito; Daniel P. Schachtman; Rekha Seshadri; Ashley Shade; David Sherman; Rachel Simister; Holly Simon; James Stegen; Ramunas Stepanauskas; Matthew Sullivan; Dawn Y. Sumner; Hanno Teeling; Kimberlee Thamatrakoln; Kathleen Treseder; Susannah Tringe; Parag Vaishampayan; David L. Valentine; Nicholas B. Waldo; Mark P. Waldrop; David A. Walsh; David M. Ward; Michael Wilkins; Thea Whitman; Jamie Woolet; Tanja Woyke; Ioannis Iliopoulos; Konstantinos Konstantinidis; James M. Tiedje; Jennifer Pett-Ridge; David Baker; Axel Visel; Christos A. Ouzounis; Sergey Ovchinnikov; Aydin Buluç; Nikos C. Kyrpides

doi:10.1038/s41586-023-06583-7

Unraveling the functional dark matter through global metagenomics

Georgios A. Pavlopoulos, Fotis A. Baltoumas, Sirui Liu, Oguz Selvitopi, Antonio Pedro Camargo, Stephen Nayfach, Ariful Azad, Simon Roux, Lee Call, Natalia N. Ivanova, I. Min Chen, David Paez-Espino, Evangelos Karatzas, Silvia G. Acinas, Nathan Ahlgren, Graeme Attwood, Petr Baldrian, Timothy Berry, Jennifer M. Bhatnagar, Devaki BhayaKay D. Bidle, Jeffrey L. Blanchard, Eric S. Boyd, Jennifer L. Bowen, Jeff Bowman, Susan H. Brawley, Eoin L. Brodie, Andreas Brune, Donald A. Bryant, Alison Buchan, Hinsby Cadillo-Quiroz, Barbara J. Campbell, Ricardo Cavicchioli, Peter F. Chuckran, Maureen Coleman, Sean Crowe, Daniel R. Colman, Cameron R. Currie, Jeff Dangl, Nathalie Delherbe, Vincent J. Denef, Paul Dijkstra, Daniel D. Distel, Emiley Eloe-Fadrosh, Kirsten Fisher, Christopher Francis, Aaron Garoutte, Amelie Gaudin, Lena Gerwick, Filipa Godoy-Vitorino, Peter Guerra, Jiarong Guo, Mussie Y. Habteselassie, Steven J. Hallam, Roland Hatzenpichler, Ute Hentschel, Matthias Hess, Ann M. Hirsch, Laura A. Hug, Jenni Hultman, Dana E. Hunt, Marcel Huntemann, William P. Inskeep, Timothy Y. James, Janet Jansson, Eric R. Johnston, Marina Kalyuzhnaya, Charlene N. Kelly, Robert M. Kelly, Jonathan L. Klassen, Klaus Nüsslein, Joel E. Kostka, Steven Lindow, Erik Lilleskov, Mackenzie Lynes, Rachel Mackelprang, Francis M. Martin, Olivia U. Mason, R. Michael McKay, Katherine McMahon, David A. Mead, Monica Medina, Laura K. Meredith, Thomas Mock, William W. Mohn, Mary Ann Moran, Alison Murray, Josh D. Neufeld, Rebecca Neumann, Jeanette M. Norton, Laila P. Partida-Martinez, Nicole Pietrasiak, Dale Pelletier, T. B.K. Reddy, Brandi Kiel Reese, Nicholas J. Reichart, Rebecca Reiss, Mak A. Saito, Daniel P. Schachtman, Rekha Seshadri, Ashley Shade, David Sherman, Rachel Simister, Holly Simon, James Stegen, Ramunas Stepanauskas, Matthew Sullivan, Dawn Y. Sumner, Hanno Teeling, Kimberlee Thamatrakoln, Kathleen Treseder, Susannah Tringe, Parag Vaishampayan, David L. Valentine, Nicholas B. Waldo, Mark P. Waldrop, David A. Walsh, David M. Ward, Michael Wilkins, Thea Whitman, Jamie Woolet, Tanja Woyke, Ioannis Iliopoulos, Konstantinos Konstantinidis, James M. Tiedje, Jennifer Pett-Ridge, David Baker, Axel Visel, Christos A. Ouzounis, Sergey Ovchinnikov, Aydin Buluç, Nikos C. Kyrpides

Department of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	594-602
Number of pages	9
Journal	Nature
Volume	622
Issue number	7983
DOIs	https://doi.org/10.1038/s41586-023-06583-7
State	Published - Oct 11 2023

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Pavlopoulos, G. A., Baltoumas, F. A., Liu, S., Selvitopi, O., Camargo, A. P., Nayfach, S., Azad, A., Roux, S., Call, L., Ivanova, N. N., Chen, I. M., Paez-Espino, D., Karatzas, E., Acinas, S. G., Ahlgren, N., Attwood, G., Baldrian, P., Berry, T., Bhatnagar, J. M., ... Kyrpides, N. C. (2023). Unraveling the functional dark matter through global metagenomics. Nature, 622(7983), 594-602. https://doi.org/10.1038/s41586-023-06583-7

Pavlopoulos, GA, Baltoumas, FA, Liu, S, Selvitopi, O, Camargo, AP, Nayfach, S, Azad, A, Roux, S, Call, L, Ivanova, NN, Chen, IM, Paez-Espino, D, Karatzas, E, Acinas, SG, Ahlgren, N, Attwood, G, Baldrian, P, Berry, T, Bhatnagar, JM, Bhaya, D, Bidle, KD, Blanchard, JL, Boyd, ES, Bowen, JL, Bowman, J, Brawley, SH, Brodie, EL, Brune, A, Bryant, DA, Buchan, A, Cadillo-Quiroz, H, Campbell, BJ, Cavicchioli, R, Chuckran, PF, Coleman, M, Crowe, S, Colman, DR, Currie, CR, Dangl, J, Delherbe, N, Denef, VJ, Dijkstra, P, Distel, DD, Eloe-Fadrosh, E, Fisher, K, Francis, C, Garoutte, A, Gaudin, A, Gerwick, L, Godoy-Vitorino, F, Guerra, P, Guo, J, Habteselassie, MY, Hallam, SJ, Hatzenpichler, R, Hentschel, U, Hess, M, Hirsch, AM, Hug, LA, Hultman, J, Hunt, DE, Huntemann, M, Inskeep, WP, James, TY, Jansson, J, Johnston, ER, Kalyuzhnaya, M, Kelly, CN, Kelly, RM, Klassen, JL, Nüsslein, K, Kostka, JE, Lindow, S, Lilleskov, E, Lynes, M, Mackelprang, R, Martin, FM, Mason, OU, McKay, RM, McMahon, K, Mead, DA, Medina, M, Meredith, LK, Mock, T, Mohn, WW, Moran, MA, Murray, A, Neufeld, JD, Neumann, R, Norton, JM, Partida-Martinez, LP, Pietrasiak, N, Pelletier, D, Reddy, TBK, Reese, BK, Reichart, NJ, Reiss, R, Saito, MA, Schachtman, DP, Seshadri, R, Shade, A, Sherman, D, Simister, R, Simon, H, Stegen, J, Stepanauskas, R, Sullivan, M, Sumner, DY, Teeling, H, Thamatrakoln, K, Treseder, K, Tringe, S, Vaishampayan, P, Valentine, DL, Waldo, NB, Waldrop, MP, Walsh, DA, Ward, DM, Wilkins, M, Whitman, T, Woolet, J, Woyke, T, Iliopoulos, I, Konstantinidis, K, Tiedje, JM, Pett-Ridge, J, Baker, D, Visel, A, Ouzounis, CA, Ovchinnikov, S, Buluç, A & Kyrpides, NC 2023, 'Unraveling the functional dark matter through global metagenomics', Nature, vol. 622, no. 7983, pp. 594-602. https://doi.org/10.1038/s41586-023-06583-7

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AU - Guerra, Peter

AU - Guo, Jiarong

AU - Habteselassie, Mussie Y.

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AU - McKay, R. Michael

AU - McMahon, Katherine

AU - Mead, David A.

AU - Medina, Monica

AU - Meredith, Laura K.

AU - Mock, Thomas

AU - Mohn, William W.

AU - Moran, Mary Ann

AU - Murray, Alison

AU - Neufeld, Josh D.

AU - Neumann, Rebecca

AU - Norton, Jeanette M.

AU - Partida-Martinez, Laila P.

AU - Pietrasiak, Nicole

AU - Pelletier, Dale

AU - Reddy, T. B.K.

AU - Reese, Brandi Kiel

AU - Reichart, Nicholas J.

AU - Reiss, Rebecca

AU - Saito, Mak A.

AU - Schachtman, Daniel P.

AU - Seshadri, Rekha

AU - Shade, Ashley

AU - Sherman, David

AU - Simister, Rachel

AU - Simon, Holly

AU - Stegen, James

AU - Stepanauskas, Ramunas

AU - Sullivan, Matthew

AU - Sumner, Dawn Y.

AU - Teeling, Hanno

AU - Thamatrakoln, Kimberlee

AU - Treseder, Kathleen

AU - Tringe, Susannah

AU - Vaishampayan, Parag

AU - Valentine, David L.

AU - Waldo, Nicholas B.

AU - Waldrop, Mark P.

AU - Walsh, David A.

AU - Ward, David M.

AU - Wilkins, Michael

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AU - Visel, Axel

AU - Ouzounis, Christos A.

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Unraveling the functional dark matter through global metagenomics

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